Top 10 Pharma companies in the world

The pharmaceutical industry consists of businesses that work on the creation, production, marketing, and distribution of traditional herbal medicines, medical equipment, and cosmetics in addition to chemical and biological pharmaceuticals for human and animal use. Statista estimates that the value of the world pharmaceutical market was close to US$1.3 trillion in 2019.

The forecast for the sector is still favourable because successive years are expected to see continuing expansion around the globe. The top 10 pharmaceutical firms in the world by revenue are listed below. These businesses have had a significant impact on the pharmaceutical industry’s current, spectacular expansion.

Here is the List of Pharmaceutical Companies which are in the top 10 in the world.

10. Moderna- (US $ 18.5 billion-2021)
09. AstraZeneca- (US $37.42 billion-2021)
08. Sanofi- (US $46.34 billion-2021)
07. Bayer- (US $ 51.30 billion-2021)
06. Novartis- (US $ 51.6 billion-2021)
05. AbbVie- (US $56.197 billion-2022)
04. Merck & Co. (MSD)- US $ 56-57 billion-2022(expected))
03. F. Hoffmann-La Roche- (US $ 68.2 billion-2021)
02. Johnson & Johnson – (US $ 96 billion-2022)
01. Pfizer- (US $ 101.3 billion-2022 (expected))

10. Moderna (Revenue: US $ 18.5 billion-2021)

Headquarters: Technology Square Cambridge, Massachusetts, U.S.
CEO: Stéphane Bancel
Founded: September 2010

How Moderna went from recording the sixth-lowest net income figure in the business to one in the black is not a secret. Sales of Spikevax, a biotech company’s mRNA COVID-19 vaccine, are credited with the transformational year for the company. Spikevax contributed $17.67 billion of the company’s $18.47 billion in revenue, and the remaining $800 million came through grant and cooperation income.

The balance sheet had lots of room for profit because expenses were less than $6.3 billion. The breakdown of those costs was as follows: $2.6 billion went toward selling, general, and administrative costs; $2 billion went into research and development; $1.1 billion went toward taxes.

Given that Moderna only produces one product, this industry-unusual low cost of sales number of 15% of product revenue can be attributed to this. For instance, businesses with wider product lines, including Pfizer (38%), AbbVie (31%), and Merck (28%), had considerably higher cost of sales in comparison to revenue.

09. AstraZeneca (Revenue: US $37.42 billion-2021)

CEO: Sir Pascal Soriot
Chairman: Leif Johansson
Headquarters: Cambridge, United Kingdom
Founded: 6 April 1999

AstraZeneca climbs all the way to ninth place in 2022 after acquiring Alexion. AstraZeneca, which has its global headquarters in Cambridge, UK, focuses on treating serious diseases, including cancer, cardiovascular, gastrointestinal, infection, neurological, respiratory, and inflammation.

AstraZeneca saw a significant 41% increase in revenues in 2021, to US$37.4 billion. With double-digit growth in all main geographies, including Emerging Markets, despite some difficult conditions in China, growth was evenly distributed among all of the company’s key areas of concentration. The corporation completed the purchase of American pharmaceutical company Alexion in July 2021, which was a major factor in growth.

Following the acquisition, rare disease medications contributed 8% of AstraZeneca’s entire 2021 sales. The company’s sales from oncology, which made up 38% of total revenue in 2021, increased by 19%. The effects of Covid-19 on diagnostic and treatment rates were partially negated by higher reimbursement and commercialization. Covid-19 vaccine was introduced in January 2021 by AstraZeneca and Oxford University, and more than 2.5 billion doses have since been made available for distribution globally.

In 2021, product sales came to $3,917 million USD. Evoshield, a product that AstraZeneca also introduced and which has proven successful in developing countries and Europe, was authorised by the FDA to prevent Covid-19 in persons with compromised immune systems. By supporting its several blockbuster medications, continuing to invest in the clinical stage pipeline, and working on strategic clinical stage business development, AstraZeneca intends to generate growth through innovation in the future.

08. Sanofi (Revenue: US $46.34 billion-2021)

Headquarters: Paris, France
CEO: Paul Hudson
Founded:20 August 2004

The French business began 2022 with a branding makeover in anticipation of concluding phase III testing of its Covid-19 vaccine soon. Sanofi strengthened its early pipeline in 2021 with 36 projects in phases I–II and received 8 “significant” approvals in the US and EU for Dupixent, Libtayo, Sarclisa, and Nexviazyme. For the first time ever, the speciality care business unit overtook vaccinations as the largest by sales.

“Dupixent®, which continues to produce remarkable record sales quarter after quarter, drove high double-digit revenue growth for Sanofi as the business closed 2021 with a strong fourth quarter result. Specialty Care has never previously outperformed our GBUs in terms of sales, marking a key turning point in our transformation, according to CEO Paul Hudson.

07. Bayer (Revenue: US $ 51.30 billion-2021)

Headquarters: Leverkusen, Germany
CEO: Werner Baumann
Founded:1 August 1863, Barmen, Germany

Bayer, one of the top pharmaceutical companies in 2022, has been on an investment binge, spending USD 2 billion to acquire a San Diego-based biotech company as well as production facilities in Latin America and Norway. This comes after a challenging 2020 and with more obstacles in the near future. Even though Bayer hasn’t yet released its 2021 financial results, its first nine months of the year saw a 5% growth.

Despite still being the company’s largest revenue generator (18,840 million euros in 2020), the Crop Science segment is also its biggest source of stress. In addition to acquiring the American pesticide and agricultural biotech company Monsanto when Bayer acquired it three years ago for a staggering USD 63 billion in cash, the company also acquired a legal dispute that is anticipated to cost USD 9.6 billion.

06. Novartis (Revenue: US $ 51.6 billion-2021)

CEO:Vasant Narasimhan
Headquarters: Basel, Switzerland
Founded: December 1996

A healthcare firm with its headquarters in Switzerland, Novartis, is ranked fifth on our list of the top pharmaceutical corporations in the world. Novartis offers solutions to meet the changing demands of patients around the world. The business not only researches and creates ground-breaking cures, but also new strategies to deliver them to as many people as possible. A total of 47.5 billion dollars in sales were made by Novartis in 2019; of that amount, 17.9 billion dollars, or 37.73 percent, were made in Europe.

05. AbbVie (Revenue: US $56.197 billion-2022)

CEO: Richard A. Gonzalez
Headquarters: North Chicago, Illinois, United States
Founder: S Nikhil Kumar
Founded:1^st January,2013; Delaware, United States

AbbVie has recently been a rising revenue giant thanks to M&A and its Humira cash cow for autoimmune illnesses. A check at the company’s earnings, though, reveals that it has also reached its stride on that metric. A net profit margin of almost 21% was achieved by AbbVie last year, which reported net income of $11.55 billion on $56.2 billion in revenues. AbbVie’s profits increased by 150% from year to year, surpassing the company’s net earnings of $4.62 billion in 2020.

Regarding the cost breakdown, AbbVie reported in an annual filing that its cost of products sold increased by roughly $2 billion from the previous year to $17.45 billion. Its selling, general, and administrative expenses increased by nearly $1 billion to $12.23 billion, and its R&D spending increased by roughly $500 million to $7.08 billion.

In total, the corporation spent $38.27 billion on operating costs in 2021, an 11% increase from the $34.44 billion in 2020. However, because AbbVie’s revenues increased significantly more than that rise, the business nonetheless generated a sizeable profit increase for shareholders. The company reported year-over-year sales growth of 22.6% earlier this year, with growth across its franchises in immunology, hematologic cancer, aesthetics, eye care, neurosciences, and more.

04. Merck & Co. (MSD) (Revenue: US $ 56-57 billion-2022(expected))

CEO: Robert M. Davis
Headquarters: Rahway, New Jersey, U.S.
Founder: Friedrich Jacob Merck
Founded:1668, Darmstadt, Germany

Merck & Co. (MSD internationally) is another company whose patents on important goods are about to expire. Keytruda, the company’s blockbuster PD-1 drug, for instance, generated USD 17.2 billion in Rx sales in 2021 and has accumulated a long list of applications, although it will lose its patent protection in 2028.

After shelving its two COVID-19 vaccine candidates, MSD had a challenging 2020–2021, but it changed course to focus on creating medications to treat the illness. Along with it, long-time CEO Kenneth Frazier announced his retirement from the company after almost 30 years of service and was replaced by Robert M. Davis.

03. F. Hoffmann-La Roche (Revenue: US $ 68.2 billion-2021)

Headquarters: Basel, Switzerland
CEO: Severin Schwan
Founder: Fritz Hoffmann-La Roche
Founded:1896, Basel, Switzerland

On our ranking of the top 10 pharmaceutical firms in the world, F. Hoffmann-La Roche, a multinational healthcare company with a focus on research, comes in at number 4. The company has made it a priority to improve lives ever since it was founded in 1896. Roche now develops novel drugs and diagnostic procedures that benefit millions of patients worldwide.

With 17 biopharmaceuticals already on the market, Roche is the global leader in biotech and the greatest spender on pharmaceutical research & development. Basel, Switzerland serves as the home office for Roche. The business, which is the largest in Switzerland and the second-largest by sales in the world, has yearly revenue of 63.85 billion US dollars (61.47 billion Swiss francs) in 2019.

02. Johnson & Johnson (Revenue: US $ 96 billion)

Headquarters: United States
CEO: Alex Gorsky
Founded: January 1886

On the list of top pharmaceutical corporations for this year, Johnson & Johnson, usually known as J&J, comes at second. Johnson & Johnson, one of the biggest pharmaceutical companies in the world, is a manufacturer of pharmaceuticals, medical equipment, and consumer health products with its corporate headquarters in New Jersey. The FDA also granted emergency use approval for J&J’s single-dose Covid-19 vaccine in the first quarter of 2021, which helped the company’s pharmaceutical segment experience rapid growth and generate US$2.3 billion in sales.

Remicade, a medication for inflammatory illnesses with an immunological component, had a lacklustre performance, which mitigated this. The position of Johnson & Johnson’s new CEO was filled by Joaquin Duato in January 2022. We are well-positioned for success in 2022 and beyond, he said during J&J’s full-year earnings call, given our outstanding results, financial profile, and creative pipeline.

01. Pfizer (Revenue: US $ 101.3 billion 2022 (expected))

CEO: Albert Bourla
Founded:1849
Headquarters: United States
Founders: Charles Pfizer, Charles F. Erhart

After moving up from sixth place in 2021 Pfizer has reached first in 2022. Pfizer is a market leader when it comes to the creation of medications and vaccines for a range of medical disciplines, including immunology, cancer, cardiology, and neurology. Their sales decreased by 19% in the previous year as a result of Upjohn’s spin-off, which was finalised in Q4 2020. Since that time, the business has developed into a single, innovative biopharmaceutical company focusing on product research, development, manufacturing, marketing, sales, and distribution on a global scale.

Thanks to its best-selling product Comirnaty, a Covid-19 vaccine, which generated sales of approximately US$37 billion for the fiscal year 2021, Pfizer’s sales raced to an astonishing US$79.6 billion with year-over-year increase up 90%. Pfizer has dedicated a significant portion of its efforts over the past two years to finding ways to combat the Covid-19 pandemic, which has greatly improved their standing within the pharmaceutical sector. Pfizer, along with their partner BioNTech, was the first business to successfully create a vaccine against COVID-19 in 2020. The Comirnaty vaccine has been administered to millions of individuals worldwide since it was authorised for use in emergencies, saving countless lives in the process.

Looking ahead, Covid-19 vaccine technology, or messenger RNA, will be aggressively expanded by the business through a partnership with Beam Therapeutics to treat uncommon genetic illnesses of the liver, muscles, and central nervous system, according to plans made public by CEO Albert Bourla. The business has also partnered with BioNTech once more to create a shingles vaccine that will reportedly be the first mRNA-based vaccination to combat the condition.

FAQs

Q.1-What are the top 10 pharma companies in the world?

10. Moderna- (US $ 18.5 billion-2021)
09. AstraZeneca- (US $37.42 billion-2021)
08. Sanofi- (US $46.34 billion-2021)
07. Bayer- (US $ 51.30 billion-2021)
06. Novartis- (US $ 51.6 billion-2021)
05. AbbVie- (US $56.197 billion-2022)
04. Merck & Co. (MSD)- US $ 56-57 billion-2022(expected))
03. F. Hoffmann-La Roche- (US $ 68.2 billion-2021.
02. Johnson & Johnson – (US $ 96 billion-2022)
01. Pfizer- (US $ 101.3 billion-2022 (expected))

Q.2- Which is the largest pharmaceutical company in the world in 2023?

Pfizer

After moving up from sixth place in 2021 Pfizer has reached first in 2022 and is likely to maintain this position in 2023. Pfizer is a market leader when it comes to the creation of medications and vaccines for a range of medical disciplines, including immunology, cancer, cardiology, and neurology. Their sales decreased by 19% in the previous year as a result of Upjohn’s spin-off, which was finalised in Q4 2020. Since that time, the business has developed into a single, innovative biopharmaceutical company focusing on product research, development, manufacturing, marketing, sales, and distribution on a global scale.

Q3- Which city is the world’s pharmaceutical capital?

Hyderabad

In addition to information technology, one of the key industries in and surrounding Hyderabad is pharmaceuticals. Hyderabad has been dubbed the “Bulk Drug Capital of India” and the “Vaccine Capital of the World” because it produces more than 40% of the nation’s bulk drugs.

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Top 10 Pharma companies in the world